⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9074439 | 0.78 | — | — | |
| SCHEMBL17076789 | 0.78 | — | — | |
| SCHEMBL5023125 | 0.75 | — | — | |
| SCHEMBL3380351 | 0.73 | — | — | |
| SCHEMBL22563598 | 0.73 | — | — | |
| SCHEMBL14929004 | 0.73 | — | — | |
| SCHEMBL26324169 | 0.73 | — | — | |
| SCHEMBL16584772 | 0.72 | — | — | |
| SCHEMBL10927295 | 0.71 | — | — | |
| SCHEMBL10924911 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115322991-A | Factor XII, kallikrein B, plasma Freuey factor 1 and kininogen 1 iRNA compositions and methods of use thereof | 阿尔尼拉姆医药品有限公司 | 2022-11-11 | — | — | CN | disclosed |