Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | G6PD | P11413 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.61 |
| ▸ | TYR | P14679 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA4 | P22748 | 2/20 | 0.53 |
| ▸ | CA5A | P35218 | 2/20 | 0.53 |
| ▸ | CA7 | P43166 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA3 | P07451 | 1/20 | 0.53 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29420858 | 1.00 | KDM4E (0.61) | KDM4EPOLBGAAMAPTG6PD | |
| SCHEMBL15641935 | 0.88 | PTGS1 (0.48) | KDM4EPOLBGAAMAPTG6PD | |
| SCHEMBL15641934 | 0.88 | PTGS1 (0.48) | KDM4EPOLBGAAMAPTG6PD | |
| SCHEMBL2835425 | 0.88 | PTGS1 (0.48) | KDM4EPOLBGAAMAPTG6PD | |
| SCHEMBL10936650 | 0.88 | PTGS1 (0.48) | KDM4EPOLBGAAMAPTG6PD | |
| SCHEMBL24529121 | 0.88 | PTGS1 (0.48) | KDM4EPOLBGAAMAPTG6PD | |
| SCHEMBL10936641 | 0.88 | PTGS1 (0.48) | KDM4EPOLBGAAMAPTG6PD | |
| SCHEMBL28223754 | 0.88 | PTGS1 (0.48) | KDM4EPOLBGAAMAPTG6PD | |
| SCHEMBL5906465 | 0.86 | GAA (0.56) | KDM4EPOLBGAAMAPTG6PD | |
| SCHEMBL29892234 | 0.86 | PTGS1 (0.56) | KDM4EPOLBGAAMAPTG6PD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111943996-B | Trachelospermi analogue, genetic engineering bacterium for producing same and application thereof | 中国科学院天津工业生物技术研究所 | 2022-03-08 | — | — | CN | disclosed |
| CN-111943996-A | Trachelospermi analogue, genetic engineering bacterium for producing same and application thereof | 中国科学院天津工业生物技术研究所 | 2020-11-17 | — | — | CN | disclosed |