SCHEMBL28911754 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	GSK3B	P49841	19/20	0.45

▸	GSK3A	P49840	18/20	0.45

▸	PIM1	P11309	2/20	0.39

▸	JAK2	O60674	1/20	0.39

▸	CDK2	P24941	1/20	0.39

▸	TYK2	P29597	1/20	0.39

▸	SYK	P43405	1/20	0.39

▸	CDK5	Q00535	1/20	0.39

▸	PRKCQ	Q04759	1/20	0.39

▸	AURKB	Q96GD4	1/20	0.39

▸	PIM3	Q86V86	1/20	0.38

▸	PIM2	Q9P1W9	1/20	0.38

▸	MAPT	P10636	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL28911765	0.93	GSK3A (0.48)	GSK3BGSK3APIM1JAK2CDK2
SCHEMBL28911762	0.89	GSK3B (0.47)	GSK3BGSK3APIM1JAK2CDK2
SCHEMBL28911787	0.89	GSK3B (0.47)	GSK3BGSK3APIM1JAK2CDK2
SCHEMBL28911714	0.89	GSK3B (0.47)	GSK3BGSK3APIM1JAK2CDK2
SCHEMBL28911756	0.87	GSK3A (0.44)	GSK3BGSK3APIM1JAK2CDK2
SCHEMBL28911722	0.87	GSK3A (0.45)	GSK3BGSK3APIM1JAK2CDK2
SCHEMBL20204938	0.85	GSK3B (0.64)	GSK3BGSK3AMAPT
SCHEMBL28911721	0.84	GSK3A (0.44)	GSK3BGSK3APIM1JAK2CDK2
SCHEMBL28911760	0.82	GSK3A (0.43)	GSK3BGSK3APIM1JAK2CDK2
SCHEMBL28911746	0.82	GSK3A (0.52)	GSK3BGSK3APIM1JAK2CDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-110545817-B	GSK-3 inhibitors	百时美施贵宝公司	2022-11-15	—	—	CN	disclosed