Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 20/20 | 1.00 |
| ▸ | FGFR1 | P11362 | 6/20 | 0.80 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.79 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20094096 | 0.94 | FGFR4 (1.00) | FGFR4FGFR1FGFR2FGFR3CYP3A4 | |
| SCHEMBL28554912 | 0.91 | FGFR4 (1.00) | FGFR4FGFR1FGFR2FGFR3CYP3A4 | |
| SCHEMBL20094042 | 0.90 | FGFR4 (1.00) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL18131723 | 0.89 | FGFR4 (1.00) | FGFR4FGFR1FGFR2FGFR3CYP3A4 | |
| SCHEMBL28911971 | 0.88 | FGFR4 (1.00) | FGFR4FGFR1FGFR2FGFR3CYP3A4 | |
| SCHEMBL20094112 | 0.88 | FGFR4 (1.00) | FGFR4FGFR1FGFR2FGFR3CYP3A4 | |
| SCHEMBL28566310 | 0.88 | FGFR4 (1.00) | FGFR4FGFR1FGFR2FGFR3CYP3A4 | |
| SCHEMBL20094043 | 0.86 | FGFR4 (1.00) | FGFR4FGFR1FGFR2FGFR3CYP3A4 | |
| SCHEMBL20094103 | 0.84 | FGFR4 (0.78) | FGFR4FGFR1FGFR2FGFR3CYP3A4 | |
| SCHEMBL20094099 | 0.84 | FGFR4 (0.82) | FGFR4FGFR1FGFR2FGFR3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108503593-B | 2-aminopyrimidine compounds and application thereof | 暨南大学 | 2021-04-27 | — | — | CN | claimed |
| CN-108503593-B | 2-aminopyrimidine compounds and application thereof | 暨南大学 | 2021-04-27 | — | — | CN | disclosed |