Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28948140 | 0.92 | CA12 (0.39) | HCRTR1HCRTR2CA12CA1CA9 | |
| SCHEMBL28913107 | 0.90 | CA12 (0.40) | HCRTR1HCRTR2CA12CA1CA9 | |
| SCHEMBL28913061 | 0.82 | HCRTR1 (0.38) | HCRTR1HCRTR2CA12CA1CA9 | |
| SCHEMBL25529191 | 0.80 | CA12 (0.42) | HCRTR1HCRTR2CA12CA1CA9 | |
| SCHEMBL13907633 | 0.80 | CA12 (0.49) | HCRTR1HCRTR2CA12CA1CA9 | |
| SCHEMBL12072363 | 0.80 | CA12 (0.49) | HCRTR1HCRTR2CA12CA1CA9 | |
| SCHEMBL15897920 | 0.79 | CA12 (0.41) | HCRTR1HCRTR2CA12CA1CA9 | |
| SCHEMBL18821375 | 0.79 | CA12 (0.43) | HCRTR1HCRTR2CA12CA1CA9 | |
| SCHEMBL15897919 | 0.79 | AAK1 (0.45) | HCRTR1HCRTR2CA12CA1CA9 | |
| SCHEMBL13035973 | 0.79 | CA12 (0.43) | HCRTR1HCRTR2CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115315423-A | Substituted aryl compounds | 先声药业有限公司 | 2022-11-08 | — | — | CN | disclosed |