Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.55 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.55 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | BRD4 | O60885 | 1/20 | 0.54 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28913289 | 1.00 | HSD17B10 (0.57) | HSD17B10PIK3CDPIK3R1PIK3CAPIK3CG | |
| SCHEMBL28574704 | 0.94 | KDM4E (0.61) | HSD17B10PIK3CDPIK3R1PIK3CAPIK3CG | |
| SCHEMBL28574706 | 0.94 | KDM4E (0.61) | HSD17B10PIK3CDPIK3R1PIK3CAPIK3CG | |
| SCHEMBL28566041 | 0.93 | HSD17B10 (0.57) | HSD17B10PIK3CDPIK3R1PIK3CAPIK3CG | |
| SCHEMBL28566039 | 0.93 | HSD17B10 (0.57) | HSD17B10PIK3CDPIK3R1PIK3CAPIK3CG | |
| SCHEMBL28569129 | 0.92 | KDM4E (0.62) | HSD17B10PIK3CDPIK3R1PIK3CAPIK3CG | |
| SCHEMBL28562751 | 0.92 | PIK3CG (0.59) | HSD17B10PIK3CDPIK3R1PIK3CAPIK3CG | |
| SCHEMBL28562752 | 0.92 | PIK3CG (0.59) | HSD17B10PIK3CDPIK3R1PIK3CAPIK3CG | |
| SCHEMBL28557557 | 0.92 | KDM4E (0.62) | HSD17B10PIK3CDPIK3R1PIK3CAPIK3CG | |
| SCHEMBL28557555 | 0.92 | KDM4E (0.62) | HSD17B10PIK3CDPIK3R1PIK3CAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112824389-B | Acrylic ketone derivative of N-acetylnorfloxacin and preparation method and application thereof | 河南大学 | 2023-08-15 | — | — | CN | disclosed |
| CN-112824389-A | Acrylone derivative of N-acetylnorfloxacin, and preparation method and application thereof | 河南大学 | 2021-05-21 | — | — | CN | disclosed |