Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28688547 | 1.00 | NR1H2 (0.64) | NR1H2HSD17B10JAK1JAK2HPGD | |
| SCHEMBL16962257 | 1.00 | NR1H2 (0.64) | NR1H2HSD17B10JAK1JAK2HPGD | |
| SCHEMBL2978266 | 1.00 | NR1H2 (0.64) | NR1H2HSD17B10JAK1JAK2HPGD | |
| SCHEMBL16042198 | 1.00 | NR1H2 (0.64) | NR1H2HSD17B10JAK1JAK2HPGD | |
| SCHEMBL22629774 | 1.00 | NR1H2 (0.64) | NR1H2HSD17B10JAK1JAK2HPGD | |
| Hydrochloric Acid SCHEMBL2977900 | 0.98 | NR1H2 (0.62) | NR1H2HSD17B10JAK1JAK2HPGD | |
| SCHEMBL25336257 | 0.95 | NR1H2 (0.58) | NR1H2HSD17B10JAK1JAK2HPGD | |
| SCHEMBL6745591 | 0.91 | NR1H2 (0.57) | NR1H2HSD17B10JAK1JAK2HPGD | |
| SCHEMBL31045773 | 0.91 | NR1H2 (0.57) | NR1H2HSD17B10JAK1JAK2HPGD | |
| SCHEMBL342765 | 0.88 | NR1H2 (0.55) | NR1H2HSD17B10JAK1JAK2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113767092-B | Di-heterocyclic carbonyl substituted dihydropyrazoles, their preparation and their use in medicine | 劲方医药科技(上海)有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-113717161-B | Nitrogen-containing saturated heterocyclic compound, preparation method thereof, pharmaceutical composition and application | 广州费米子科技有限责任公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-113149996-B | Polycyclic amide derivative as CDK9 inhibitor, and preparation method and application thereof | 苏州阿尔脉生物科技有限公司 | 2022-12-20 | — | — | CN | disclosed |