Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.71 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28914925 | 1.00 | MEN1 (0.71) | MEN1KMT2ARXFP1POLBMAPT | |
| SCHEMBL28915828 | 0.95 | MEN1 (0.76) | MEN1KMT2ARXFP1POLBMAPT | |
| SCHEMBL28576478 | 0.95 | MEN1 (0.76) | MEN1KMT2ARXFP1POLBMAPT | |
| SCHEMBL10175701 | 0.91 | KMT2A (0.62) | MEN1KMT2ARXFP1POLBLMNA | |
| SCHEMBL28584658 | 0.91 | KMT2A (0.62) | MEN1KMT2ARXFP1POLBMAPT | |
| SCHEMBL28583977 | 0.91 | KMT2A (0.62) | MEN1KMT2ARXFP1POLBMAPT | |
| SCHEMBL29768501 | 0.91 | KMT2A (0.62) | MEN1KMT2ARXFP1POLBMAPT | |
| SCHEMBL29768421 | 0.91 | KMT2A (0.62) | MEN1KMT2ARXFP1POLBMAPT | |
| SCHEMBL28574002 | 0.89 | POLB (0.61) | MEN1KMT2ARXFP1POLBMAPT | |
| SCHEMBL28582449 | 0.89 | POLB (0.61) | MEN1KMT2ARXFP1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112778154-B | Aryl alkyl ether compound and derivative thereof, preparation method, pharmaceutical composition and application | 中国药科大学 | 2022-05-13 | — | — | CN | claimed |
| CN-112778154-A | Aryl alkyl ether compound and derivative thereof, preparation method, pharmaceutical composition and application | 中国药科大学 | 2021-05-11 | — | — | CN | claimed |
| CN-112778154-B | Aryl alkyl ether compound and derivative thereof, preparation method, pharmaceutical composition and application | 中国药科大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-112778154-A | Aryl alkyl ether compound and derivative thereof, preparation method, pharmaceutical composition and application | 中国药科大学 | 2021-05-11 | — | — | CN | disclosed |