Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALB | P02768 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3443920 | 1.00 | MCHR1 (0.46) | MCHR1CA12CA2CA9ALDH1A1 | |
| SCHEMBL8744438 | 1.00 | MCHR1 (0.46) | MCHR1CA12CA2CA9ALDH1A1 | |
| SCHEMBL9144466 | 1.00 | MCHR1 (0.46) | MCHR1CA12CA2CA9ALDH1A1 | |
| SCHEMBL8949575 | 1.00 | MCHR1 (0.46) | MCHR1CA12CA2CA9ALDH1A1 | |
| SCHEMBL9060708 | 0.98 | CA12 (0.45) | MCHR1CA12CA2CA9ALDH1A1 | |
| SCHEMBL9227919 | 0.98 | CA12 (0.45) | MCHR1CA12CA2CA9ALDH1A1 | |
| SCHEMBL9060692 | 0.98 | CA12 (0.45) | MCHR1CA12CA2CA9ALDH1A1 | |
| SCHEMBL4209138 | 0.94 | CA12 (0.46) | MCHR1CA12CA2CA9ALDH1A1 | |
| SCHEMBL31370679 | 0.94 | CA12 (0.46) | MCHR1CA12CA2CA9ALDH1A1 | |
| SCHEMBL4209136 | 0.94 | CA12 (0.46) | MCHR1CA12CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112261970-A | 3- (5-hydroxy-1-oxoisoindolin-2-yl) piperidine-2, 6-dione derivatives and their use in the treatment of IKAROS family Zinc finger 2(IKZF2) dependent diseases | 诺华股份有限公司 | 2021-01-22 | — | — | CN | disclosed |