Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 9/20 | 0.72 |
| ▸ | AXL | P30530 | 3/20 | 0.68 |
| ▸ | PTK2 | Q05397 | 5/20 | 0.62 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.58 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.58 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.58 |
| ▸ | AURKA | O14965 | 1/20 | 0.57 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.57 |
| ▸ | INSR | P06213 | 1/20 | 0.57 |
| ▸ | IGF1R | P08069 | 1/20 | 0.57 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.57 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.57 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30184441 | 1.00 | EGFR (0.72) | EGFRAXLPTK2MAPK8MAPK9 | |
| SCHEMBL28917519 | 0.92 | EGFR (0.74) | EGFRAXLPTK2MAPK8MAPK9 | |
| SCHEMBL30184335 | 0.92 | EGFR (0.74) | EGFRAXLPTK2MAPK8MAPK9 | |
| SCHEMBL28594506 | 0.85 | EGFR (0.84) | EGFRAXLPTK2MAPK8MAPK9 | |
| SCHEMBL28589740 | 0.84 | EGFR (0.82) | EGFRAXLPTK2MAPK8MAPK9 | |
| SCHEMBL28601123 | 0.83 | EGFR (0.80) | EGFRAXLPTK2MAPK8MAPK9 | |
| SCHEMBL28589461 | 0.83 | EGFR (0.81) | EGFRAXLPTK2MAPK8MAPK9 | |
| SCHEMBL28589929 | 0.81 | EGFR (0.79) | EGFRAXLPTK2MAPK8MAPK9 | |
| SCHEMBL12964728 | 0.81 | AXL (1.00) | EGFRAXLAURKAAURKBIGF1R | |
| SCHEMBL28586392 | 0.81 | EGFR (0.73) | EGFRAXLPTK2MAPK8MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113061117-B | 2- ((5-chloro-2- (4-morpholine methylanilino) pyrimidine-4-yl) amino) benzamide derivative | 长治学院 | 2023-02-10 | — | — | CN | disclosed |
| CN-113061117-A | 2- ((5-chloro-2- (4-morpholine methylanilino) pyrimidine-4-yl) amino) benzamide derivative | 长治学院 | 2021-07-02 | — | — | CN | disclosed |