Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24000834 | 0.84 | ENPP1 (0.69) | ENPP1HRH1 | |
| Hydrochloric Acid SCHEMBL30088839 | 0.83 | ENPP1 (0.68) | ENPP1HRH1 | |
| SCHEMBL24000850 | 0.83 | ENPP1 (0.75) | ENPP1LMNASMN1; SMN2HTTGAA | |
| Hydrochloric Acid SCHEMBL30088949 | 0.82 | ENPP1 (0.73) | ENPP1LMNASMN1; SMN2HTTGAA | |
| SCHEMBL24000639 | 0.79 | ENPP1 (0.59) | ENPP1LMNASMN1; SMN2HTTGAA | |
| SCHEMBL28917095 | 0.78 | ENPP1 (0.62) | ENPP1LMNASMN1; SMN2HTTGAA | |
| Hydrochloric Acid SCHEMBL31384257 | 0.78 | ENPP1 (0.68) | ENPP1 | |
| Hydrochloric Acid SCHEMBL28917094 | 0.78 | ENPP1 (0.68) | ENPP1LMNASMN1; SMN2HTTGAA | |
| Hydrochloric Acid SCHEMBL31384211 | 0.78 | ENPP1 (0.59) | ENPP1LMNASMN1; SMN2HTTGAA | |
| Hydrochloric Acid SCHEMBL30088972 | 0.78 | ENPP1 (0.68) | ENPP1LMNASMN1; SMN2HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515939-A | Novel phthalazine derivatives having an inhibitory activity on ectonucleotide pyrophosphatase-phosphodiesterase and their use | 谛希诺生物科技有限公司 | 2022-12-23 | — | — | CN | claimed |
| CN-115515939-A | Novel phthalazine derivatives having an inhibitory activity on ectonucleotide pyrophosphatase-phosphodiesterase and their use | 谛希诺生物科技有限公司 | 2022-12-23 | — | — | CN | disclosed |