Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.47 |
| ▸ | CMA1 | P23946 | 3/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.45 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.45 |
| ▸ | NMUR1 | Q9HB89 | 2/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28918709 | 1.00 | ACE (0.51) | ACEACE2SLC6A2OPRD1OPRM1 | |
| SCHEMBL18373909 | 0.97 | ACE (0.48) | ACEACE2SLC6A2OPRD1OPRM1 | |
| SCHEMBL20415547 | 0.97 | ACE (0.48) | ACEACE2SLC6A2OPRD1OPRM1 | |
| SCHEMBL18373948 | 0.97 | ACE (0.48) | ACEACE2SLC6A2OPRD1OPRM1 | |
| SCHEMBL20415534 | 0.97 | ACE (0.48) | ACEACE2SLC6A2OPRD1OPRM1 | |
| SCHEMBL18373952 | 0.92 | ACE (0.52) | ACEACE2SLC6A2OPRD1OPRM1 | |
| SCHEMBL28918691 | 0.92 | ACE (0.52) | ACEACE2SLC6A2OPRD1OPRM1 | |
| SCHEMBL28918898 | 0.91 | ACE (0.58) | ACEACE2OPRD1OPRM1NMUR2 | |
| SCHEMBL18373944 | 0.91 | ACE (0.58) | ACEACE2OPRD1OPRM1NMUR2 | |
| SCHEMBL28918719 | 0.88 | ACE (0.56) | ACEACE2OPRD1OPRM1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115368438-A | Pyrrolidine amide derivatives and methods of making and using the same | 成均馆大学校产学协力团 | 2022-11-22 | — | — | CN | disclosed |