Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3295915 | 0.92 | KDM4E (0.64) | KDM4EMAPTMEN1ALOX15KMT2A | |
| SCHEMBL510854 | 0.85 | MAPT (0.54) | KDM4EMAPTMEN1ALOX15KMT2A | |
| SCHEMBL3295918 | 0.85 | KDM4E (0.56) | KDM4EMAPTMEN1ALOX15KMT2A | |
| SCHEMBL14963199 | 0.82 | KDM4E (0.53) | KDM4EMAPTMEN1ALOX15KMT2A | |
| SCHEMBL30987784 | 0.81 | KDM4E (0.86) | KDM4EMAPTMEN1ALOX15KMT2A | |
| SCHEMBL14963235 | 0.81 | KDM4E (0.62) | KDM4EMAPTMEN1ALOX15KMT2A | |
| SCHEMBL9695763 | 0.80 | KDM4E (0.51) | KDM4EMAPTMEN1ALOX15KMT2A | |
| SCHEMBL11578007 | 0.80 | KDM4E (0.50) | KDM4EMAPTMEN1ALOX15KMT2A | |
| SCHEMBL13461890 | 0.79 | MAPT (0.50) | KDM4EMAPTMEN1ALOX15KMT2A | |
| SCHEMBL14963232 | 0.78 | KDM4E (0.62) | KDM4EMAPTMEN1ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113173884-B | Method for synthesizing pyridine and derivative thereof by catalyzing hans ester 1, 4-dihydropyridine compound with titanocene dichloride | 陕西师范大学 | 2023-08-15 | — | — | CN | disclosed |
| CN-113173884-A | Method for synthesizing pyridine and derivatives thereof by catalyzing hans ester 1, 4-dihydropyridine compounds with titanocene dichloride | 陕西师范大学 | 2021-07-27 | — | — | CN | disclosed |