Acetic Acid

Acetic Acid

SCHEMBL28919486

CC(=O)O.N=[N+]=N.N=[N+]=N.N=[N+]=N.N=[N+]=N.OCC(CO)(CO)CO

nearest known ligand 0.39

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Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.39
LCK P06239 1/20 0.39
FYN P06241 1/20 0.39
ALDH1A1 P00352 3/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HIF1A Q16665 1/20 0.33
TSHR P16473 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL813642 0.88 FFAR3 (0.50) FFAR3LCKFYNALDH1A1TP53
Acetic Acid SCHEMBL725625 0.88 FFAR3 (0.50) FFAR3LCKFYNALDH1A1TP53
Acetic Acid SCHEMBL11544701 0.88 FFAR3 (0.50) FFAR3LCKFYNALDH1A1TP53
Acetic Acid SCHEMBL2578973 0.88 FFAR3 (0.50) FFAR3LCKFYNALDH1A1TP53
Acetic Acid SCHEMBL28959399 0.88 FFAR3 (0.50) FFAR3LCKFYNALDH1A1TP53
Acetic Acid SCHEMBL309352 0.88 FFAR3 (0.50) FFAR3LCKFYNALDH1A1TP53
Acetic Acid SCHEMBL10338273 0.88 FFAR3 (0.50) FFAR3LCKFYNALDH1A1TP53
Acetic Acid SCHEMBL832778 0.88 FFAR3 (0.50) FFAR3LCKFYNALDH1A1TP53
Acetic Acid SCHEMBL27896643 0.80 FFAR3 (0.41) FFAR3LCKFYNALDH1A1TP53
Acetic Acid SCHEMBL28446125 0.79 FFAR3 (0.47) FFAR3LCKFYNALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115521455-A Preparation method of polytriazole polyether elastomer 北京理工大学 2022-12-27 CN claimed
CN-115521451-A Preparation method of propiolate-terminated polyether 北京理工大学 2022-12-27 CN claimed
CN-115521455-A Preparation method of polytriazole polyether elastomer 北京理工大学 2022-12-27 CN disclosed
CN-115521451-A Preparation method of propiolate-terminated polyether 北京理工大学 2022-12-27 CN disclosed