Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TET2 | Q6N021 | 6/20 | 0.42 |
| ▸ | KDM4A | O75164 | 2/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.42 |
| ▸ | TET3 | O43151 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | PGK2 | P07205 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL21753470 | 0.91 | — | — | |
| SCHEMBL584528 | 0.91 | — | — | |
| SCHEMBL38462 | 0.91 | — | — | |
| SCHEMBL2905876 | 0.91 | — | — | |
| Water SCHEMBL10757023 | 0.91 | — | — | |
| SCHEMBL29597490 | 0.91 | — | — | |
| SCHEMBL29278852 | 0.91 | OR51E2 (1.00) | OR51E2SMN1; SMN2TET2KDM4AKDM4C | |
| SCHEMBL1765577 | 0.91 | OR51E2 (1.00) | OR51E2SMN1; SMN2TET2KDM4AKDM4C | |
| SCHEMBL9251246 | 0.88 | OR51E2 (0.93) | OR51E2SMN1; SMN2TET2KDM4AKDM4C | |
| SCHEMBL10789759 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108570468-B | Nucleic acids comprising or encoding a histone stem-loop and a polyadenylation sequence or polyadenylation signal to increase expression of a gene encoding a therapeutic protein | 库瑞瓦格股份公司 | 2022-11-25 | — | — | CN | disclosed |