SCHEMBL28922787

SCHEMBL28922787

OCc1ccc2c(c1)OCC=C2

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STS P08842 1/20 0.45
CYP3A4 P08684 2/20 0.33
CYP2D6 P10635 1/20 0.33
PDE5A O76074 1/20 0.32
CYP2B6 P20813 1/20 0.31
PDCD1 Q15116 4/20 0.31
CD274 Q9NZQ7 4/20 0.31
CA12 O43570 1/20 0.31
CA2 P00918 1/20 0.31
CA3 P07451 1/20 0.31
CA4 P22748 1/20 0.31
CA6 P23280 1/20 0.31
CA5A P35218 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
CA14 Q9ULX7 1/20 0.31
CA5B Q9Y2D0 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
BAD Q92934 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28222960 0.82 STS (0.49) STSCYP2B6CD274CA12CA2
SCHEMBL13072315 0.82 STS (0.45) STSCYP2B6NPC1RAB9A
SCHEMBL22096140 0.78 STS (0.42) STS
SCHEMBL6956052 0.77 STS (0.44) STSCYP2D6
SCHEMBL6956048 0.77 STS (0.45) STS
SCHEMBL30779639 0.76 STS (0.57) STSCYP2B6CA2CA5ACA7
SCHEMBL29771885 0.76 STS (0.49) STSCYP3A4CYP2B6CA12CA2
SCHEMBL547263 0.76 STS (0.49) STSCYP3A4CYP2B6CA12CA2
SCHEMBL5534601 0.74 STS (0.40) STS
SCHEMBL27629608 0.74 STS (0.46) STSCYP3A4CYP2B6CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115521325-A Boronic acid derivatives 首药控股(北京)股份有限公司 2022-12-27 CN disclosed