Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | GRM8 | O00222 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30065165 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP2A6HRH1HTR2ATBXAS1 | |
| SCHEMBL24919476 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP2A6HRH1HTR2ATBXAS1 | |
| SCHEMBL28924921 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP2A6HRH1HTR2ATBXAS1 | |
| SCHEMBL6074158 | 0.85 | SMN1; SMN2 (0.57) | SMN1; SMN2CFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6074090 | 0.85 | SMN1; SMN2 (0.57) | SMN1; SMN2CFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1609153 | 0.85 | SMN1; SMN2 (0.57) | SMN1; SMN2CFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2577931 | 0.84 | SMN1; SMN2 (0.52) | SMN1; SMN2TBXAS1CFTRSLC6A2SLC6A4 | |
| SCHEMBL26772791 | 0.84 | SMN1; SMN2 (0.52) | SMN1; SMN2TBXAS1CFTRSLC6A2SLC6A4 | |
| SCHEMBL26772785 | 0.84 | SMN1; SMN2 (0.52) | SMN1; SMN2TBXAS1CFTRSLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL6285618 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2CYP2A6CFTRSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113387925-B | Preparation method for synthesizing S-nicotine from glutarate | 深圳市真味生物科技有限公司 | 2023-03-28 | — | — | CN | claimed |
| CN-113475739-B | Preparation method of S-nicotine | 深圳市真味生物科技有限公司 | 2022-11-11 | — | — | CN | claimed |
| CN-113475739-A | Preparation method of S-nicotine | 深圳市真味生物科技有限公司 | 2021-10-08 | — | — | CN | claimed |
| CN-113387925-A | Preparation method for synthesizing S-nicotine from glutarate | 深圳市真味生物科技有限公司 | 2021-09-14 | — | — | CN | claimed |
| CN-113582972-B | Method for synthesizing chiral nicotine from butyrolactone | 深圳市真味生物科技有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-113387925-B | Preparation method for synthesizing S-nicotine from glutarate | 深圳市真味生物科技有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-113387925-B | Preparation method for synthesizing S-nicotine from glutarate | 深圳市真味生物科技有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-113475739-B | Preparation method of S-nicotine | 深圳市真味生物科技有限公司 | 2022-11-11 | — | — | CN | disclosed |
| CN-113475739-B | Preparation method of S-nicotine | 深圳市真味生物科技有限公司 | 2022-11-11 | — | — | CN | disclosed |
| CN-113582972-A | Method for synthesizing chiral nicotine from butyrolactone | 深圳市真味生物科技有限公司 | 2021-11-02 | — | — | CN | disclosed |
| CN-113475739-A | Preparation method of S-nicotine | 深圳市真味生物科技有限公司 | 2021-10-08 | — | — | CN | disclosed |
| CN-113475739-A | Preparation method of S-nicotine | 深圳市真味生物科技有限公司 | 2021-10-08 | — | — | CN | disclosed |
| CN-113387925-A | Preparation method for synthesizing S-nicotine from glutarate | 深圳市真味生物科技有限公司 | 2021-09-14 | — | — | CN | disclosed |
| CN-113387925-A | Preparation method for synthesizing S-nicotine from glutarate | 深圳市真味生物科技有限公司 | 2021-09-14 | — | — | CN | disclosed |