SCHEMBL28925328

SCHEMBL28925328

CCCCCCOP(=O)(O)OC[C@H]1O[C@@H](n2ccc(N)nc2=O)C[C@@H]1O

nearest known ligand 0.66

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.66
P2RY2 P41231 6/20 0.59
P2RY4 P51582 3/20 0.59
P2RY6 Q15077 3/20 0.59
PLA2G1B P04054 1/20 0.53
ATG4B Q9Y4P1 1/20 0.53
POLG P54098 1/20 0.50
NT5E P21589 1/20 0.45
ADK P55263 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31206612 1.00 POLB (0.66) POLBP2RY2P2RY4P2RY6PLA2G1B
SCHEMBL17877166 1.00 POLB (0.66) POLBP2RY2P2RY4P2RY6PLA2G1B
SCHEMBL10053783 0.95 POLB (0.67) POLBP2RY2P2RY4P2RY6PLA2G1B
SCHEMBL26233311 0.89 POLB (0.54) POLBP2RY2P2RY4P2RY6PLA2G1B
SCHEMBL13127046 0.88 POLB (0.67) POLBP2RY2P2RY4P2RY6POLG
SCHEMBL13111591 0.88 POLB (0.67) POLBP2RY2P2RY4P2RY6POLG
SCHEMBL145870 0.88 POLB (0.67) POLBP2RY2P2RY4P2RY6POLG
SCHEMBL5413913 0.87 POLB (0.59) POLBP2RY2P2RY4P2RY6PLA2G1B
SCHEMBL5155763 0.87 POLB (0.59) POLBP2RY2P2RY4P2RY6PLA2G1B
SCHEMBL12961599 0.87 POLB (0.73) POLBP2RY2P2RY4P2RY6POLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4704831-A2 SUBSTITUTED PYRIMIDINONE AND AZAPYRIMIDINONE COMPOUNDS, COMPOSITIONS, AND USES THEREOF Lakewood Amedex, Inc. (US) 2026-03-11 EP disclosed
WO-2024226983-A2 SUBSTITUTED PYRIMIDINONE AND AZAPYRIMIDINONE COMPOUNDS, COMPOSITIONS, AND USES THEREOF Lakewood Amedex, Inc. (US) 2024-10-31 WO disclosed
CN-115552033-A Sequencing method of biopolymer 代表亚利桑那大学的亚利桑那校董事会 2022-12-30 CN disclosed