Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.82 |
| ▸ | MEN1 | O00255 | 3/20 | 0.82 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.82 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.67 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | TACR1 | P25103 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | NMBR | P28336 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | BMP1 | P13497 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28926425 | 1.00 | KMT2A (0.82) | KMT2AMEN1HCRTR1NPBWR1MCHR1 | |
| SCHEMBL10942408 | 0.96 | KMT2A (0.79) | KMT2AMEN1HCRTR1NPBWR1MCHR1 | |
| SCHEMBL19051477 | 0.89 | KMT2A (0.82) | KMT2AMEN1HCRTR1NPBWR1MCHR1 | |
| SCHEMBL21001594 | 0.89 | KMT2A (0.81) | KMT2AMEN1HCRTR1NPBWR1MCHR1 | |
| SCHEMBL21001595 | 0.89 | KMT2A (0.81) | KMT2AMEN1HCRTR1NPBWR1MCHR1 | |
| SCHEMBL31520097 | 0.89 | KMT2A (0.81) | KMT2AMEN1HCRTR1NPBWR1MCHR1 | |
| SCHEMBL21001391 | 0.88 | KMT2A (0.80) | KMT2AMEN1HCRTR1NPBWR1MCHR1 | |
| SCHEMBL21001325 | 0.88 | KMT2A (0.80) | KMT2AMEN1HCRTR1NPBWR1MCHR1 | |
| SCHEMBL16621132 | 0.88 | KMT2A (0.80) | KMT2AMEN1HCRTR1NPBWR1MCHR1 | |
| SCHEMBL21001156 | 0.88 | KMT2A (0.80) | KMT2AMEN1HCRTR1NPBWR1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115385846-A | Indole compound, preparation method and application thereof | 复旦大学 | 2022-11-25 | — | — | CN | disclosed |