Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.42 |
| ▸ | CYCS | P99999 | 3/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.38 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29358276 | 0.99 | TOP1 (0.43) | TOP1CYCSMMP2MMP9MMP8 | |
| SCHEMBL140683 | 0.99 | TOP1 (0.43) | TOP1CYCSMMP2MMP9MMP8 | |
| SCHEMBL11341449 | 0.97 | TOP1 (0.42) | TOP1CYCSMMP2MMP9MMP8 | |
| SCHEMBL28492100 | 0.97 | TOP1 (0.42) | TOP1CYCSMMP2MMP9MMP8 | |
| SCHEMBL28650010 | 0.97 | TOP1 (0.42) | TOP1CYCSMMP2MMP9MMP8 | |
| SCHEMBL11293563 | 0.97 | TOP1 (0.42) | TOP1CYCSMMP2MMP9MMP8 | |
| SCHEMBL28351380 | 0.97 | TOP1 (0.42) | TOP1CYCSMMP2MMP9MMP8 | |
| Hydrochloric Acid SCHEMBL16188274 | 0.97 | KDM4E (0.43) | TOP1CYCSMMP2MMP9MMP8 | |
| SCHEMBL30632112 | 0.97 | TOP1 (0.42) | TOP1CYCSMMP2MMP9MMP8 | |
| SCHEMBL28452941 | 0.97 | TOP1 (0.42) | TOP1CYCSMMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115536859-B | Porphyrin metal-organic framework material based on bimetallic oxygen chain and preparation method and application thereof | 中山大学 | 2023-03-14 | — | — | CN | disclosed |
| CN-115536859-A | Porphyrin metal-organic framework material based on bimetallic oxygen chain and preparation method and application thereof | 中山大学 | 2022-12-30 | — | — | CN | disclosed |