Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28927234 | 1.00 | MAPK1 (0.50) | MAPK1NPC1RAB9ASMN1; SMN2TAAR1 | |
| SCHEMBL29256447 | 1.00 | MAPK1 (0.50) | MAPK1NPC1RAB9ASMN1; SMN2TAAR1 | |
| SCHEMBL31037188 | 0.84 | NPC1 (0.50) | MAPK1NPC1RAB9ASMN1; SMN2TAAR1 | |
| SCHEMBL14154795 | 0.84 | NPC1 (0.50) | MAPK1NPC1RAB9ASMN1; SMN2TAAR1 | |
| SCHEMBL14821250 | 0.84 | NPC1 (0.50) | MAPK1NPC1RAB9ASMN1; SMN2TAAR1 | |
| SCHEMBL29040569 | 0.80 | CYP1A2 (0.44) | MAPK1NPC1RAB9ASMN1; SMN2TAAR1 | |
| SCHEMBL1338546 | 0.79 | NPC1 (0.61) | MAPK1NPC1RAB9ASMN1; SMN2TAAR1 | |
| SCHEMBL15842376 | 0.78 | MAPT (0.58) | NPC1RAB9ASMN1; SMN2TAAR1CYP1A2 | |
| SCHEMBL30636781 | 0.78 | MAPT (0.58) | NPC1RAB9ASMN1; SMN2TAAR1CYP1A2 | |
| SCHEMBL28927198 | 0.78 | MAPT (0.58) | NPC1RAB9ASMN1; SMN2TAAR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116396203-B | Preparation method of 2-hydroxy-indol-3-one compound | 五邑大学 | 2025-03-25 | — | — | CN | disclosed |
| CN-116396203-A | Preparation method of 2-hydroxy-indol-3-one compound | 五邑大学 | 2023-07-07 | — | — | CN | disclosed |
| CN-115397824-A | Process for preparing COT inhibitor compounds | 吉利德科学公司 | 2022-11-25 | — | — | CN | disclosed |