Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.76 |
| ▸ | MAOA | P21397 | 4/20 | 0.73 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.72 |
| ▸ | ACHE | P22303 | 4/20 | 0.65 |
| ▸ | BCHE | P06276 | 1/20 | 0.64 |
| ▸ | CES2 | O00748 | 2/20 | 0.63 |
| ▸ | MIF | P14174 | 4/20 | 0.60 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30413593 | 1.00 | MAOB (0.76) | MAOBMAOACYP19A1ACHEBCHE | |
| SCHEMBL28927416 | 0.92 | MAOB (0.84) | MAOBMAOACYP19A1ACHEBCHE | |
| SCHEMBL30413650 | 0.92 | MAOB (0.84) | MAOBMAOACYP19A1ACHEBCHE | |
| SCHEMBL6990912 | 0.92 | MAOB (0.84) | MAOBMAOACYP19A1ACHEBCHE | |
| SCHEMBL28927347 | 0.88 | MAOB (0.78) | MAOBMAOACYP19A1ACHEBCHE | |
| SCHEMBL30412163 | 0.88 | MAOB (0.78) | MAOBMAOACYP19A1ACHEBCHE | |
| SCHEMBL28927385 | 0.86 | MAOB (0.76) | MAOBMAOACYP19A1ACHEBCHE | |
| SCHEMBL5581835 | 0.86 | MAOB (0.76) | MAOBMAOACYP19A1ACHEBCHE | |
| SCHEMBL30412903 | 0.86 | MAOB (0.76) | MAOBMAOACYP19A1ACHEBCHE | |
| SCHEMBL5581839 | 0.86 | MAOB (0.76) | MAOBMAOACYP19A1ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115417871-B | Double spiro pyrrolospirone oxindole compound, synthesis method and antifungal activity thereof | 成都理工大学 | 2023-06-02 | — | — | CN | claimed |
| CN-115417871-A | Double-spiro pyrrole spiro oxindole compound and synthesis method and antifungal activity thereof | 成都理工大学 | 2022-12-02 | — | — | CN | claimed |
| CN-115417871-B | Double spiro pyrrolospirone oxindole compound, synthesis method and antifungal activity thereof | 成都理工大学 | 2023-06-02 | — | — | CN | disclosed |
| CN-115417871-A | Double-spiro pyrrole spiro oxindole compound and synthesis method and antifungal activity thereof | 成都理工大学 | 2022-12-02 | — | — | CN | disclosed |