Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 11/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 11/20 | 0.45 |
| ▸ | APH1B | Q8WW43 | 11/20 | 0.45 |
| ▸ | NCSTN | Q92542 | 11/20 | 0.45 |
| ▸ | APH1A | Q96BI3 | 11/20 | 0.45 |
| ▸ | PSENEN | Q9NZ42 | 11/20 | 0.45 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30059657 | 1.00 | PSEN1 (0.45) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL28927994 | 0.91 | PSEN1 (0.45) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL30058107 | 0.91 | PSEN1 (0.45) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL28962180 | 0.91 | C5AR1 (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL30057618 | 0.89 | C5AR1 (0.53) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL28928039 | 0.89 | C5AR1 (0.53) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL30059432 | 0.88 | PSEN1 (0.48) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL28928044 | 0.88 | PSEN1 (0.48) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL28858222 | 0.85 | PSEN1 (0.61) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL29143146 | 0.83 | C5AR1 (0.50) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115557893-A | Preparation method of sulfonyl-substituted 8-membered benzo [ b ] azepine Xin Huanhua compound | 烟台大学 | 2023-01-03 | — | — | CN | claimed |
| CN-115557893-A | Preparation method of sulfonyl-substituted 8-membered benzo [ b ] azepine Xin Huanhua compound | 烟台大学 | 2023-01-03 | — | — | CN | disclosed |