SCHEMBL28929323

SCHEMBL28929323

CC(=O)NC(=O)c1ccccc1Cl

nearest known ligand 0.64

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.64
TSHR P16473 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.58
HPGD P15428 4/20 0.56
CYP1A2 P05177 1/20 0.56
CYP2C19 P33261 1/20 0.56
MAPT P10636 2/20 0.55
KDM4E B2RXH2 1/20 0.54
RECQL P46063 1/20 0.54
CES2 O00748 1/20 0.54
CES1 P23141 1/20 0.54
ALDH1A1 P00352 3/20 0.53
KMT2A Q03164 2/20 0.53
LMNA P02545 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10593626 1.00 POLB (0.64) POLBTSHRL3MBTL1HPGDCYP1A2
SCHEMBL304416 0.83 POLB (0.69) POLBTSHRL3MBTL1HPGDCYP1A2
SCHEMBL11593314 0.82 POLB (0.81) POLBTSHRL3MBTL1HPGDCYP1A2
SCHEMBL11121630 0.82 POLB (0.56) POLBTSHRL3MBTL1HPGDCYP1A2
SCHEMBL5166894 0.82 POLB (0.56) POLBTSHRL3MBTL1HPGDCYP1A2
SCHEMBL19893245 0.82 POLB (0.67) POLBTSHRL3MBTL1HPGDCYP1A2
SCHEMBL28921918 0.81 POLB (0.50) POLBTSHRL3MBTL1HPGDCYP1A2
SCHEMBL9005579 0.80 POLB (0.55) POLBTSHRL3MBTL1HPGDCYP1A2
SCHEMBL9782063 0.80 POLB (0.64) POLBTSHRL3MBTL1HPGDCYP1A2
SCHEMBL9118696 0.80 POLB (0.64) POLBTSHRL3MBTL1HPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115557849-A Method for synthesizing imide compound under induction of NBS and water by visible light 西南大学 2023-01-03 CN disclosed