Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMIGD3 | P0DMS9 | 3/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.56 |
| ▸ | TLR7 | Q9NYK1 | 16/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3134008 | 0.99 | TMIGD3 (0.55) | TMIGD3ADORA2AADORA2BADORA1TLR7 | |
| SCHEMBL4461897 | 0.88 | TLR7 (0.53) | TMIGD3ADORA2AADORA2BADORA1TLR7 | |
| SCHEMBL18563916 | 0.88 | ADORA2A (0.61) | TMIGD3ADORA2AADORA2BADORA1TLR7 | |
| SCHEMBL18584238 | 0.86 | ADORA2A (0.59) | TMIGD3ADORA2AADORA2BADORA1TLR7 | |
| SCHEMBL7209091 | 0.86 | ADORA2A (0.74) | TMIGD3ADORA2AADORA2BADORA1TLR7 | |
| SCHEMBL7209457 | 0.83 | ADORA2A (0.72) | TMIGD3ADORA2AADORA2BADORA1TLR7 | |
| SCHEMBL3122899 | 0.82 | TMIGD3 (0.56) | TMIGD3ADORA2AADORA2BADORA1TLR7 | |
| SCHEMBL4468323 | 0.82 | TLR7 (0.57) | TLR7 | |
| SCHEMBL15726056 | 0.82 | TMIGD3 (0.55) | TMIGD3ADORA2AADORA2BADORA1TLR7 | |
| Bromide SCHEMBL31308120 | 0.81 | TLR7 (0.56) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116457023-A | antibody-TLR agonist conjugates, methods and uses thereof | AMBRX公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-113660957-A | Compositions, methods, and uses comprising antibody-TLR agonist conjugates | AMBRX公司 | 2021-11-16 | — | — | CN | disclosed |