Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 8/20 | 0.53 |
| ▸ | SRC | P12931 | 7/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.53 |
| ▸ | KIT | P10721 | 2/20 | 0.53 |
| ▸ | FLT3 | P36888 | 2/20 | 0.53 |
| ▸ | SIK1 | P57059 | 1/20 | 0.53 |
| ▸ | RIPK4 | P57078 | 1/20 | 0.53 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.53 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.53 |
| ▸ | DSTYK | Q6XUX3 | 1/20 | 0.53 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.53 |
| ▸ | ABL1 | P00519 | 6/20 | 0.44 |
| ▸ | EGFR | P00533 | 6/20 | 0.44 |
| ▸ | ABL2 | P42684 | 6/20 | 0.44 |
| ▸ | NEK7 | Q8TDX7 | 2/20 | 0.43 |
| ▸ | LCK | P06239 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 2/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | PRKCG | P05129 | 1/20 | 0.40 |
| ▸ | PRKCB | P05771 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28929651 | 1.00 | RIPK2 (0.53) | RIPK2SRCPDGFRBKITFLT3 | |
| SCHEMBL30569234 | 0.94 | ABL1 (0.53) | RIPK2SRCPDGFRBKITFLT3 | |
| SCHEMBL28670225 | 0.94 | ABL1 (0.53) | RIPK2SRCPDGFRBKITFLT3 | |
| SCHEMBL28655844 | 0.89 | SRC (0.66) | RIPK2SRCPDGFRBKITFLT3 | |
| SCHEMBL28655842 | 0.89 | SRC (0.66) | RIPK2SRCPDGFRBKITFLT3 | |
| SCHEMBL28656676 | 0.85 | SRC (0.48) | RIPK2SRCPDGFRBKITFLT3 | |
| SCHEMBL30569231 | 0.85 | SRC (0.48) | RIPK2SRCPDGFRBKITFLT3 | |
| SCHEMBL28669572 | 0.84 | EGFR (0.56) | RIPK2SRCABL1EGFRABL2 | |
| SCHEMBL28669568 | 0.84 | EGFR (0.56) | RIPK2SRCABL1EGFRABL2 | |
| SCHEMBL23966925 | 0.83 | RIPK2 (0.72) | RIPK2SRCPDGFRBKITFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113683629-B | Substituted heteroaryl compounds, compositions and uses thereof | 北京范恩柯尔生物科技有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-113683629-A | Substituted heteroaryl compounds, compositions and uses thereof | 北京范恩柯尔生物科技有限公司 | 2021-11-23 | — | — | CN | disclosed |