Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | JAK3 | P52333 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | SUV39H2 | Q9H5I1 | 7/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | CKS1B | P61024 | 1/20 | 0.46 |
| ▸ | SKP1 | P63208 | 1/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.46 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.45 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.45 |
| ▸ | ITGAL | P20701 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28930758 | 1.00 | PDE10A (0.49) | PDE10AJAK3BTKSUV39H2PIM1 | |
| SCHEMBL4476430 | 0.91 | PDE10A (0.46) | PDE10AJAK3BTKSUV39H2PIM1 | |
| SCHEMBL1351739 | 0.83 | PDE10A (0.55) | PDE10APIM1PIM3PIM2SYK | |
| SCHEMBL1351743 | 0.83 | PDE10A (0.55) | PDE10APIM1PIM3PIM2SYK | |
| SCHEMBL15401351 | 0.81 | BTK (0.55) | PDE10AJAK3BTKSUV39H2SYK | |
| SCHEMBL3820924 | 0.80 | CKS1B (0.53) | PDE10AJAK3BTKSUV39H2SYK | |
| SCHEMBL24166014 | 0.79 | MAP4K4 (0.59) | PDE10AJAK3BTKSUV39H2PIM1 | |
| SCHEMBL3929667 | 0.78 | MAP4K4 (0.51) | PDE10AJAK3BTKSUV39H2PIM1 | |
| SCHEMBL31124502 | 0.78 | SUV39H2 (0.47) | SUV39H2PIM1PIM3PIM2SYK | |
| SCHEMBL28603266 | 0.78 | SUV39H2 (0.47) | SUV39H2PIM1PIM3PIM2SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115557946-A | Heterocyclic lactam compound, pharmaceutical composition containing same and application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-01-03 | — | — | CN | disclosed |