Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 15/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.52 |
| ▸ | PPARD | Q03181 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10076908 | 0.89 | FFAR1 (0.53) | FFAR1PPARGFFAR4PPARDALDH1A1 | |
| SCHEMBL10077182 | 0.88 | PPARD (0.44) | FFAR1PPARGFFAR4PPARDALDH1A1 | |
| SCHEMBL2912655 | 0.88 | FFAR1 (0.54) | FFAR1PPARGFFAR4PPARDALDH1A1 | |
| SCHEMBL10077727 | 0.88 | FFAR1 (0.54) | FFAR1PPARGFFAR4 | |
| SCHEMBL10077238 | 0.87 | FFAR1 (0.51) | FFAR1PPARGFFAR4PPARDALDH1A1 | |
| SCHEMBL12894897 | 0.86 | FFAR1 (0.56) | FFAR1PPARGFFAR4ALDH1A1 | |
| SCHEMBL10077240 | 0.86 | FFAR1 (0.52) | FFAR1PPARGFFAR4ALDH1A1TSHR | |
| SCHEMBL225088 | 0.83 | FFAR1 (0.76) | FFAR1 | |
| SCHEMBL10077721 | 0.83 | FFAR1 (0.52) | FFAR1PPARGFFAR4PPARDALDH1A1 | |
| SCHEMBL10064988 | 0.83 | FFAR1 (0.52) | FFAR1PPARGFFAR4PPARDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012010413-A1 | ARYLOXY-ALKYLENE SUBSTITUTED HYDROXYPHENYL HEXYNOIC ACIDS, METHODS FOR THE PRODUCTION THEREOF AND USE OF THE SAME AS MEDICAMENT | SANOFI (FR) | 2012-01-26 | — | — | WO | disclosed |