Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 9/20 | 0.78 |
| ▸ | MEN1 | O00255 | 3/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.78 |
| ▸ | PIM1 | P11309 | 2/20 | 0.78 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.78 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.62 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | IL4 | P05112 | 1/20 | 0.57 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31139635 | 1.00 | ADORA1 (0.78) | ADORA1MEN1KMT2APIM1L3MBTL1 | |
| SCHEMBL28687495 | 0.93 | MAPK14 (0.77) | ADORA1MEN1KMT2APIM1L3MBTL1 | |
| SCHEMBL31120351 | 0.87 | ADORA1 (0.83) | ADORA1MEN1KMT2APIM1L3MBTL1 | |
| SCHEMBL27886346 | 0.87 | ADORA1 (1.00) | ADORA1MEN1KMT2APIM1L3MBTL1 | |
| SCHEMBL22215734 | 0.87 | ADORA1 (1.00) | ADORA1MEN1KMT2APIM1L3MBTL1 | |
| SCHEMBL31120343 | 0.86 | ADORA1 (0.78) | ADORA1MEN1KMT2APIM1L3MBTL1 | |
| SCHEMBL31120375 | 0.86 | ADORA1 (0.78) | ADORA1MEN1KMT2APIM1L3MBTL1 | |
| SCHEMBL31139633 | 0.86 | ADORA1 (0.78) | ADORA1MEN1KMT2APIM1L3MBTL1 | |
| SCHEMBL31139632 | 0.86 | ADORA1 (0.78) | ADORA1MEN1KMT2APIM1L3MBTL1 | |
| SCHEMBL8184355 | 0.83 | IKBKB (0.65) | ADORA1MEN1KMT2APIM1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109020883-B | 3-cyano-2-aminopyridine derivative and preparation method and application thereof | 广西民族大学 | 2022-02-08 | — | — | CN | disclosed |
| CN-109020883-B | 3-cyano-2-aminopyridine derivative and preparation method and application thereof | 广西民族大学 | 2022-02-08 | — | — | CN | disclosed |