SCHEMBL2893208

SCHEMBL2893208

CCCCCCCCC1(CCCCCCCC)c2cc(N)ccc2-c2ccc(N)cc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHEK1 O14757 1/20 0.40
PRKD3 O94806 1/20 0.40
MAP4K4 O95819 1/20 0.40
RET P07949 1/20 0.40
MET P08581 1/20 0.40
PDGFRA P16234 1/20 0.40
FLT1 P17948 1/20 0.40
LTK P29376 1/20 0.40
PRKX P51817 1/20 0.40
NEK2 P51955 1/20 0.40
JAK3 P52333 1/20 0.40
BTK Q06187 1/20 0.40
MAP4K2 Q12851 1/20 0.40
DYRK1A Q13627 1/20 0.40
TAOK1 Q7L7X3 1/20 0.40
CLK4 Q9HAZ1 1/20 0.40
DYRK1B Q9Y463 1/20 0.40
TSHR P16473 1/20 0.39
CYP19A1 P11511 6/20 0.38
CNR1 P21554 6/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2776896 1.00 CHEK1 (0.40) CHEK1PRKD3MAP4K4RETMET
SCHEMBL30543304 1.00 CHEK1 (0.40) CHEK1PRKD3MAP4K4RETMET
SCHEMBL30569606 1.00 CHEK1 (0.40) CHEK1PRKD3MAP4K4RETMET
SCHEMBL30569604 1.00 CHEK1 (0.40) CHEK1PRKD3MAP4K4RETMET
SCHEMBL22228373 0.93 CHEK1 (0.41) CHEK1PRKD3MAP4K4RETMET
SCHEMBL2804322 0.92 PDK2 (0.43) CHEK1PRKD3MAP4K4RETMET
SCHEMBL30435035 0.92 PDK2 (0.43) CHEK1PRKD3MAP4K4RETMET
SCHEMBL27789288 0.92 PDK2 (0.43) CHEK1PRKD3MAP4K4RETMET
SCHEMBL28097916 0.91 CHEK1 (0.35) CHEK1PRKD3MAP4K4RETMET
SCHEMBL992489 0.91 CHEK1 (0.35) CHEK1PRKD3MAP4K4RETMET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118240341-A Thermosetting resin composition and application thereof 广东生益科技股份有限公司 2024-06-25 CN disclosed
CN-114350277-B Conductive adhesive, conductive adhesive film, and preparation method and application thereof 广东省科学院化工研究所 2023-10-13 CN disclosed
CN-116496199-A Modified maleimide compound and application thereof 广东生益科技股份有限公司 2023-07-28 CN disclosed
CN-101595155-B Block copolymer and polymer light-emitting device SUMITOMO CO LTD 2012-06-06 CN disclosed
US-7723464-B2 Aromatic/aliphatic diamine derivatives for advanced compositions and polymers THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 2010-05-25 US disclosed
US-7723464-B2 Aromatic/aliphatic diamine derivatives for advanced compositions and polymers THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 2010-05-25 US disclosed
US-20080004419-A1 Novel Aromatic/Aliphatic Diamine Derivatives For Advanced Compositions And Polymers UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPAC (US) 2008-01-03 US disclosed
US-20080004419-A1 Novel Aromatic/Aliphatic Diamine Derivatives For Advanced Compositions And Polymers UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPAC (US) 2008-01-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080004419-A1 Novel Aromatic/Aliphatic Diamine Derivatives For Advanced Compositions And Polymers MLLT3, AAAS, HNRNPDL CHEK1 438/4885PRKD3 1913/4885MAP4K4 1425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.