Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 3/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 4/20 | 0.45 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | USP7 | Q93009 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29900688 | 1.00 | TACR1 (0.55) | TACR1PDE4BRORCABL1DEGS1 | |
| SCHEMBL23951729 | 1.00 | TACR1 (0.55) | TACR1PDE4BRORCABL1DEGS1 | |
| SCHEMBL23923854 | 0.87 | ABL1 (0.48) | ABL1DEGS1GSK3BDYRK1ATRPV1 | |
| SCHEMBL23923853 | 0.87 | ABL1 (0.48) | ABL1DEGS1GSK3BDYRK1ATRPV1 | |
| SCHEMBL10165990 | 0.86 | GSK3B (0.52) | TACR1ABL1USP30GSK3BDYRK1A | |
| SCHEMBL23951809 | 0.83 | TACR1 (0.51) | TACR1PDE4BRORCTNFUSP30 | |
| SCHEMBL29900568 | 0.83 | TACR1 (0.51) | TACR1PDE4BRORCTNFUSP30 | |
| SCHEMBL23951495 | 0.82 | TACR1 (0.61) | TACR1PDE4BRORCABL1DEGS1 | |
| SCHEMBL23951349 | 0.81 | TACR1 (0.54) | TACR1PDE4BRORCUSP30USP7 | |
| SCHEMBL28932924 | 0.81 | TACR1 (0.54) | TACR1PDE4BRORCUSP30USP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427394-A | Heterocyclic compounds for modulating NR2F6 | TES制药有限责任公司 | 2022-12-02 | — | — | CN | disclosed |