Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 3/20 | 0.57 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | RORC | P51449 | 1/20 | 0.52 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23951815 | 1.00 | TACR1 (0.57) | TACR1PTPN2PTPN1PTPN6RAB9A | |
| SCHEMBL23951495 | 0.93 | TACR1 (0.61) | TACR1PTPN2PTPN1PTPN6SMN1; SMN2 | |
| SCHEMBL23951618 | 0.92 | TACR1 (0.50) | TACR1PTPN2PTPN1PTPN6RAB9A | |
| SCHEMBL29900783 | 0.92 | TACR1 (0.50) | TACR1PTPN2PTPN1PTPN6RAB9A | |
| SCHEMBL23951819 | 0.92 | TACR1 (0.50) | TACR1PTPN2PTPN1PTPN6RAB9A | |
| SCHEMBL28932948 | 0.91 | TACR1 (0.57) | TACR1PTPN2PTPN1PTPN6RAB9A | |
| SCHEMBL29900719 | 0.91 | TACR1 (0.57) | TACR1PTPN2PTPN1PTPN6RAB9A | |
| SCHEMBL23951368 | 0.91 | TACR1 (0.57) | TACR1PTPN2PTPN1PTPN6RAB9A | |
| SCHEMBL23951384 | 0.89 | TACR1 (0.51) | TACR1PTPN2PTPN1PTPN6RAB9A | |
| SCHEMBL23951821 | 0.87 | TACR1 (0.54) | TACR1PTPN2PTPN1PTPN6RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427394-A | Heterocyclic compounds for modulating NR2F6 | TES制药有限责任公司 | 2022-12-02 | — | — | CN | disclosed |