Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14977275 | 1.00 | HTT (0.42) | HTTCYP2C19CYP2C9IDO1TDO2 | |
| SCHEMBL30268853 | 1.00 | HTT (0.42) | HTTCYP2C19CYP2C9IDO1TDO2 | |
| SCHEMBL25472038 | 1.00 | HTT (0.42) | HTTCYP2C19CYP2C9IDO1TDO2 | |
| SCHEMBL28934650 | 1.00 | HTT (0.42) | HTTCYP2C19CYP2C9IDO1TDO2 | |
| SCHEMBL23526053 | 0.86 | SOS1 (0.32) | HTT | |
| SCHEMBL23525967 | 0.86 | SOS1 (0.32) | HTT | |
| SCHEMBL23526055 | 0.86 | SOS1 (0.32) | HTT | |
| SCHEMBL23525971 | 0.86 | SOS1 (0.32) | HTT | |
| SCHEMBL23525970 | 0.86 | SOS1 (0.32) | HTT | |
| SCHEMBL29945711 | 0.86 | SOS1 (0.32) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115461338-A | 3-azabicyclo (3.1.0) hexane derivatives having KDM5 inhibitory activity and uses thereof | 小野药品工业株式会社 | 2022-12-09 | — | — | CN | disclosed |