SCHEMBL28935296

SCHEMBL28935296

CC1CC(=O)C(=c2sc(=C3C(=O)CC(C)CC3=O)s2)C(=O)C1

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.39
PIK3CD O00329 1/20 0.33
PIK3CA P42336 1/20 0.33
PIK3CB P42338 1/20 0.33
PIK3CG P48736 1/20 0.33
STAT3 P40763 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7029411 0.74
SCHEMBL1073565 0.68
SCHEMBL14648600 0.67 CRBN (0.40) CRBNPIK3CDPIK3CAPIK3CBPIK3CG
SCHEMBL13196679 0.63 CRBN (0.42) CRBN
SCHEMBL20100244 0.63
SCHEMBL10958421 0.62 CRBN (0.40) CRBN
SCHEMBL1918044 0.60 CRBN (0.39) CRBN
SCHEMBL1659708 0.59 KMT2A (0.34) CRBN
SCHEMBL2044296 0.59 KMT2A (0.34) CRBN
SCHEMBL2044931 0.59 KMT2A (0.34) CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116332902-B 1, 3-Dithiacyclobutane-2, 4-dichotomous compound and synthesis and application thereof 河西学院 2024-12-24 CN disclosed
CN-116332902-A 1, 3-dithiacyclobutane-2, 4-dichotomous compound and synthesis and application thereof 河西学院 2023-06-27 CN disclosed
CN-114149408-A 1, 3-dithiolane-2, 4-subunit compound and synthesis and application thereof 河西学院 2022-03-08 CN disclosed