Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 2/20 | 0.34 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27612309 | 0.81 | NOTUM (0.32) | — | |
| SCHEMBL25295829 | 0.80 | — | — | |
| SCHEMBL105810 | 0.75 | HRH4 (0.39) | — | |
| SCHEMBL1443559 | 0.72 | ESR2 (0.39) | IDH1 | |
| SCHEMBL30267568 | 0.71 | DDB1 (0.41) | IDH1 | |
| SCHEMBL23612091 | 0.69 | KDM5A (0.36) | IDH1TRPV3JAK2JAK1TYK2 | |
| SCHEMBL29988613 | 0.69 | KDM5A (0.36) | IDH1TRPV3JAK2JAK1TYK2 | |
| SCHEMBL1002123 | 0.68 | — | — | |
| SCHEMBL17838765 | 0.66 | CACNA1B (0.30) | — | |
| SCHEMBL4772450 | 0.66 | CNR2 (0.37) | TRPV3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279770-A | Compounds and compositions for treating diseases associated with STING activity | 艾福姆德尤股份有限公司 | 2022-11-01 | — | — | CN | disclosed |