Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | PRKDC | P78527 | 2/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | TTK | P33981 | 10/20 | 0.34 |
| ▸ | RET | P07949 | 8/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.33 |
| ▸ | CDK2 | P24941 | 3/20 | 0.33 |
| ▸ | AURKA | O14965 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31484050 | 1.00 | PIK3CA (0.34) | PIK3CAPRKDCMTORTTKRET | |
| SCHEMBL29878424 | 0.85 | PIK3CA (0.34) | PIK3CAPRKDCMTORTTKRET | |
| SCHEMBL29879004 | 0.85 | PIK3CA (0.33) | PIK3CAPRKDCMTORTTKRET | |
| SCHEMBL29878089 | 0.84 | TTK (0.36) | PIK3CAPRKDCMTORTTKRET | |
| SCHEMBL31484164 | 0.83 | MAPT (0.35) | PIK3CAPRKDCMTORRET | |
| SCHEMBL28935785 | 0.83 | MAPT (0.35) | PIK3CAPRKDCMTORRET | |
| SCHEMBL30207696 | 0.83 | MAPT (0.35) | PIK3CAPRKDCMTORRET | |
| SCHEMBL31484030 | 0.81 | TTK (0.33) | PIK3CAPRKDCMTORTTKCCNA2 | |
| SCHEMBL28935696 | 0.81 | TTK (0.33) | PIK3CAPRKDCMTORTTKCCNA2 | |
| SCHEMBL31484108 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611925-A | HPK1 inhibitors and uses thereof | 轩竹生物科技股份有限公司 | 2023-01-17 | — | — | CN | disclosed |