Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 3/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GRAMD1A | Q96CP6 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31484210 | 1.00 | NR1H2 (0.56) | NR1H2ESR2MAPTMAPK1MEN1 | |
| SCHEMBL29508891 | 0.93 | NR1H2 (0.62) | NR1H2ESR2MAPTMAPK1ADORA1 | |
| SCHEMBL10255757 | 0.93 | NR1H2 (0.62) | NR1H2ESR2MAPTMAPK1ADORA1 | |
| SCHEMBL21553391 | 0.91 | NR1H2 (0.48) | NR1H2ESR2MAPTMEN1KMT2A | |
| SCHEMBL31460221 | 0.88 | ESR2 (0.54) | NR1H2ESR2MAPTMAPK1MEN1 | |
| SCHEMBL30707038 | 0.88 | ESR2 (0.54) | NR1H2ESR2MAPTMAPK1MEN1 | |
| SCHEMBL13779817 | 0.86 | NR1H2 (0.52) | NR1H2ESR2MAPTMAPK1PARP1 | |
| SCHEMBL16691229 | 0.85 | NR1H2 (0.62) | NR1H2ESR2MAPTMAPK1ADORA1 | |
| SCHEMBL2080340 | 0.84 | NR1H2 (0.56) | NR1H2ESR2MAPTADORA1NPC1 | |
| SCHEMBL30207688 | 0.84 | NR1H2 (0.56) | NR1H2ESR2MAPTADORA1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611925-A | HPK1 inhibitors and uses thereof | 轩竹生物科技股份有限公司 | 2023-01-17 | — | — | CN | disclosed |