SCHEMBL28935975

SCHEMBL28935975

COC(=O)c1cccc2[nH]c(-c3ccccc3S(=O)(=O)O)nc12

nearest known ligand 0.59

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PKN1 Q16512 2/20 0.59
PKN2 Q16513 2/20 0.59
PARP1 P09874 6/20 0.54
RIPK1 Q13546 2/20 0.47
DHODH Q02127 9/20 0.46
CDK1 P06493 1/20 0.45
KDR P35968 1/20 0.45
PLA2G2A P14555 1/20 0.44
ALOX15 P16050 1/20 0.44
PTGS2 P35354 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1170810 0.82 PKN1 (0.77) PKN1PKN2PARP1RIPK1DHODH
SCHEMBL7322715 0.79 PKN1 (0.81) PKN1PKN2PARP1DHODHPLA2G2A
SCHEMBL15528896 0.78 PARP1 (0.61) PKN1PKN2PARP1RIPK1DHODH
SCHEMBL505325 0.77 PKN1 (0.77) PKN1PKN2PARP1DHODHPLA2G2A
SCHEMBL5618837 0.76 DHODH (0.64) PKN1PKN2PARP1RIPK1DHODH
SCHEMBL270675 0.76 CA1 (0.55)
SCHEMBL29992657 0.75 KDM4E (0.51)
SCHEMBL506401 0.75 DHODH (0.59) PARP1DHODH
SCHEMBL28710749 0.74 TOP2A (0.68)
SCHEMBL28706320 0.74 PKN1 (0.69) PKN1PKN2PARP1DHODHPLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110066389-B Ionic monomer containing benzo-heterocycle sulfonate structure, flame-retardant anti-dripping ionomer using ionic monomer, and preparation methods and applications of ionic monomer and ionomer 四川大学 2022-03-15 CN disclosed