Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 20/20 | 0.47 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22744439 | 1.00 | MAP3K14 (0.47) | MAP3K14PRKD1 | |
| SCHEMBL29439508 | 1.00 | MAP3K14 (0.47) | MAP3K14PRKD1 | |
| SCHEMBL23870045 | 0.86 | MAP3K14 (0.48) | MAP3K14PRKD1 | |
| SCHEMBL22744152 | 0.86 | MAP3K14 (0.48) | MAP3K14PRKD1 | |
| SCHEMBL22715080 | 0.86 | MAP3K14 (0.43) | MAP3K14PRKD1 | |
| SCHEMBL22715084 | 0.86 | MAP3K14 (0.43) | MAP3K14PRKD1 | |
| SCHEMBL29439475 | 0.86 | MAP3K14 (0.43) | MAP3K14PRKD1 | |
| SCHEMBL29439598 | 0.84 | MAP3K14 (0.51) | MAP3K14 | |
| SCHEMBL22715936 | 0.84 | MAP3K14 (0.51) | MAP3K14 | |
| SCHEMBL22715259 | 0.82 | MAP3K14 (0.58) | MAP3K14PRKD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114222737-A | Small molecule inhibitor of NF-kB induced kinase | 詹森药业有限公司 | 2022-03-22 | — | — | CN | claimed |
| CN-114222737-A | Small molecule inhibitor of NF-kB induced kinase | 詹森药业有限公司 | 2022-03-22 | — | — | CN | disclosed |