Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 20/20 | 0.74 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.64 |
| ▸ | NTRK2 | Q16620 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2521945 | 0.86 | CCNK (0.57) | NTRK1NTRK3NTRK2 | |
| SCHEMBL15560326 | 0.81 | JAK2 (0.74) | NTRK1NTRK3NTRK2 | |
| SCHEMBL28706358 | 0.81 | NTRK1 (1.00) | NTRK1NTRK3NTRK2 | |
| SCHEMBL29392243 | 0.81 | NTRK1 (1.00) | NTRK1NTRK3NTRK2 | |
| SCHEMBL2519243 | 0.81 | CCNK (0.56) | NTRK1NTRK3NTRK2 | |
| SCHEMBL1027064 | 0.81 | PKMYT1 (0.59) | NTRK1 | |
| SCHEMBL1025466 | 0.81 | PKMYT1 (0.59) | NTRK1 | |
| SCHEMBL2522792 | 0.80 | NTRK1 (0.56) | NTRK1NTRK3NTRK2 | |
| SCHEMBL2515605 | 0.80 | NTRK1 (0.63) | NTRK1NTRK3NTRK2 | |
| SCHEMBL15545704 | 0.80 | NTRK1 (0.69) | NTRK1NTRK3NTRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114105887-B | Aminopyrimidine derivative and preparation method and application thereof | 沈阳药科大学 | 2023-12-01 | — | — | CN | disclosed |
| CN-114105887-A | Aminopyrimidine derivative and preparation method and application thereof | 沈阳药科大学 | 2022-03-01 | — | — | CN | disclosed |