SCHEMBL28936748

SCHEMBL28936748

CCC(O)(O)C(C)C.c1cc2ccc1-2

nearest known ligand 0.32

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
HPGD P15428 1/20 0.32
PTPN1 P18031 1/20 0.32
CYP17A1 P05093 3/20 0.32
CYP3A4 P08684 3/20 0.32
ALDH1A1 P00352 1/20 0.30
CYP2C19 P33261 1/20 0.30
PTGS2 P35354 1/20 0.30
MAPT P10636 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
HRH3 Q9Y5N1 1/20 0.30
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL410636 0.84
Tert-Butanol SCHEMBL27557881 0.65 ESR1 (0.44) SMN1; SMN2L3MBTL1HPGDCYP3A4ALDH1A1
Alcohol SCHEMBL2443956 0.65
SCHEMBL28719906 0.65 ESR1 (0.44) SMN1; SMN2L3MBTL1PTPN1CYP3A4ALDH1A1
Propane SCHEMBL28440529 0.64
Isobutanol SCHEMBL27627626 0.64 TSHR (0.60) SMN1; SMN2PTPN1ALDH1A1PTGS2NPC1
SCHEMBL592132 0.64
SCHEMBL3267186 0.63 SLC13A5 (0.44) SMN1; SMN2L3MBTL1HPGDALDH1A1MAPT
SCHEMBL19731918 0.63 ESR1 (0.48) CYP17A1CYP2C19MAPTNPC1RAB9A
SCHEMBL25166714 0.61 TSHR (0.30) ALDH1A1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109475120-B Antimicrobial compositions 西姆莱斯股份公司 2022-03-29 CN disclosed