Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14850502 | 0.77 | MAPK1 (0.57) | MAPK1KDM4EL3MBTL1ALDH1A1ATM | |
| SCHEMBL14782142 | 0.77 | MAPK1 (0.57) | MAPK1KDM4EL3MBTL1ALDH1A1ATM | |
| SCHEMBL4128911 | 0.77 | MAPK1 (0.57) | MAPK1KDM4EL3MBTL1ALDH1A1ATM | |
| SCHEMBL9109285 | 0.76 | MAPK1 (0.61) | MAPK1KDM4EL3MBTL1ALDH1A1TSHR | |
| SCHEMBL23031061 | 0.75 | MAPK1 (0.55) | MAPK1KDM4EL3MBTL1ALDH1A1ATM | |
| SCHEMBL63531 | 0.75 | MAPK1 (0.55) | MAPK1KDM4EL3MBTL1ALDH1A1ATM | |
| SCHEMBL27999559 | 0.75 | MAPK1 (0.55) | MAPK1KDM4EL3MBTL1ALDH1A1ATM | |
| SCHEMBL4038270 | 0.75 | MAPK1 (0.55) | MAPK1KDM4EL3MBTL1ALDH1A1ATM | |
| SCHEMBL18547783 | 0.75 | MAPK1 (0.55) | MAPK1KDM4EL3MBTL1ALDH1A1ATM | |
| SCHEMBL27282195 | 0.75 | MAPK1 (0.55) | MAPK1KDM4EL3MBTL1ALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108299420-B | Pentacyclic compounds as selective estrogen receptor down-regulators and uses thereof | 南京圣和药业股份有限公司 | 2021-10-15 | — | — | CN | disclosed |