Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 14/20 | 0.60 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20046295 | 1.00 | AR (0.60) | ARMAOBCYP19A1MAOAKDM4E | |
| SCHEMBL25059066 | 0.88 | AR (0.62) | AR | |
| SCHEMBL24379222 | 0.88 | AR (0.62) | AR | |
| SCHEMBL18473038 | 0.86 | AR (0.63) | AR | |
| SCHEMBL29817288 | 0.86 | AR (0.63) | AR | |
| SCHEMBL17162070 | 0.86 | AR (0.63) | AR | |
| SCHEMBL17162071 | 0.86 | AR (0.63) | AR | |
| SCHEMBL17941087 | 0.86 | AR (0.63) | AR | |
| SCHEMBL23536760 | 0.85 | AR (0.51) | ARKDM4EUSP2ALDH1A1 | |
| SCHEMBL23572690 | 0.85 | AR (0.51) | ARKDM4EUSP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181277-A | Chimeric compound for targeted degradation of androgen receptor protein, preparation method thereof and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2022-03-15 | — | — | CN | disclosed |