Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 14/20 | 0.54 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CFD | P00746 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27074546 | 0.90 | KLKB1 (0.53) | KLKB1F10HCRTR1HCRTR2GLA | |
| SCHEMBL20584697 | 0.90 | KLKB1 (0.52) | KLKB1F10 | |
| SCHEMBL29580856 | 0.90 | KLKB1 (0.52) | KLKB1F10 | |
| SCHEMBL20584698 | 0.90 | KLKB1 (0.52) | KLKB1F10 | |
| SCHEMBL20584700 | 0.90 | KLKB1 (0.52) | KLKB1F10 | |
| SCHEMBL28938012 | 0.84 | KLKB1 (0.76) | KLKB1F10 | |
| SCHEMBL20584573 | 0.80 | KLKB1 (0.51) | KLKB1F10CFD | |
| SCHEMBL20446447 | 0.80 | KLKB1 (0.51) | KLKB1F10CFD | |
| SCHEMBL20584575 | 0.80 | KLKB1 (0.51) | KLKB1F10CFD | |
| SCHEMBL17064969 | 0.79 | KLKB1 (0.39) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108289893-B | Human plasma kallikrein inhibitors | 拜奥克里斯特制药公司 | 2022-04-12 | — | — | CN | disclosed |