Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.39 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 3/20 | 0.36 |
| ▸ | GCG | P01275 | 2/20 | 0.36 |
| ▸ | RET | P07949 | 10/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | KIF5B | P33176 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | CCDC6 | Q16204 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28938081 | 1.00 | EGLN1 (0.39) | EGLN1ALKBH1GCGRGCGRET | |
| SCHEMBL23930123 | 0.87 | EGLN1 (0.38) | EGLN1GCGRGCGRETJAK2 | |
| SCHEMBL29275444 | 0.85 | EGLN1 (0.44) | EGLN1RETJAK2KIF5BKDR | |
| SCHEMBL29275442 | 0.85 | EGLN1 (0.44) | EGLN1RETJAK2KIF5BKDR | |
| SCHEMBL29589289 | 0.78 | EGLN1 (0.46) | EGLN1RETJAK2KIF5BKDR | |
| SCHEMBL23930237 | 0.78 | EGLN1 (0.37) | EGLN1RETJAK2KIF5BKDR | |
| SCHEMBL23929882 | 0.78 | EGLN1 (0.37) | EGLN1RETJAK2KIF5BKDR | |
| Hydrochloric Acid SCHEMBL29629385 | 0.77 | EGLN1 (0.45) | EGLN1RETJAK2KIF5BKDR | |
| SCHEMBL23930121 | 0.75 | EGLN1 (0.41) | EGLN1GCGRGCGRETJAK2 | |
| SCHEMBL23930124 | 0.75 | EGLN1 (0.41) | EGLN1GCGRGCGRETJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605477-B | Pyrazolo [1,5-a ] pyridine derivative, preparation method, composition and application thereof | 深圳众格生物科技有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-115605477-A | Pyrazolo [1,5-a ] pyridine derivative and preparation method, composition and application thereof | 深圳众格生物科技有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |