SCHEMBL28938751

SCHEMBL28938751

CC(C)(C)C(C)(C(=O)O)c1ccccc1.[CaH2]

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.52
MAPT P10636 1/20 0.48
KMT2A Q03164 1/20 0.48
CYP2C19 P33261 3/20 0.47
HIF1A Q16665 1/20 0.47
ALDH1A1 P00352 3/20 0.46
ALOX15 P16050 1/20 0.46
HDAC3 O15379 1/20 0.45
HDAC4 P56524 1/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC7 Q8WUI4 1/20 0.45
HDAC2 Q92769 1/20 0.45
HDAC10 Q969S8 1/20 0.45
HDAC11 Q96DB2 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
HDAC9 Q9UKV0 1/20 0.45
HDAC5 Q9UQL6 1/20 0.45
CYP2D6 P10635 1/20 0.44
KCNN4 O15554 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3726386 0.98 CYP1A2 (0.54) CYP1A2MAPTKMT2ACYP2C19HIF1A
SCHEMBL28727502 0.95 CYP1A2 (0.52) CYP1A2MAPTKMT2ACYP2C19HIF1A
SCHEMBL5012477 0.82 MAPT (0.48) CYP1A2MAPTKMT2ACYP2C19HIF1A
SCHEMBL1894263 0.80 CYP1A2 (0.56) CYP1A2MAPTKMT2ACYP2C19HIF1A
SCHEMBL13447969 0.80 MAPT (0.47) CYP1A2MAPTKMT2ACYP2C19HIF1A
SCHEMBL7044103 0.80 ESR1 (0.50) ALDH1A1ESR1ESR2CYP3A4TSHR
SCHEMBL2308306 0.80 MAPT (0.47) CYP1A2MAPTKMT2ACYP2C19HIF1A
SCHEMBL7037031 0.78 MEN1 (0.46) MAPTKMT2AHDAC3HDAC1HDAC2
SCHEMBL6349689 0.78 KMT2A (0.50) CYP1A2MAPTKMT2ACYP2C19HIF1A
Potassium Ion SCHEMBL28727484 0.78 KMT2A (0.45) CYP1A2MAPTKMT2ACYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110172019-B Metal salts of malonic acid as nucleating additives for crystalline thermoplastics 印度石油有限公司 2022-03-04 CN disclosed