Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | VCP | P55072 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22925691 | 0.86 | TRPV1 (0.51) | TRPV1HDAC1HDAC6VCPFLT1 | |
| SCHEMBL28733672 | 0.82 | TRPV1 (0.50) | TRPV1HDAC1HDAC6DGAT1VCP | |
| SCHEMBL22925710 | 0.81 | TRPV1 (0.47) | TRPV1HDAC1HDAC6DGAT1VCP | |
| SCHEMBL22925942 | 0.81 | TRPV1 (0.47) | TRPV1HDAC1HDAC6DGAT1VCP | |
| SCHEMBL28939281 | 0.81 | TRPV1 (0.47) | TRPV1HDAC1HDAC6DGAT1VCP | |
| SCHEMBL22925497 | 0.81 | TRPV1 (0.48) | TRPV1HDAC1HDAC6DGAT1VCP | |
| SCHEMBL29696323 | 0.81 | TRPV1 (0.48) | TRPV1HDAC1HDAC6DGAT1VCP | |
| SCHEMBL28733704 | 0.81 | TRPV1 (0.48) | TRPV1HDAC1HDAC6DGAT1VCP | |
| SCHEMBL24637017 | 0.80 | TRPV1 (0.48) | TRPV1HDAC1HDAC6DGAT1VCP | |
| SCHEMBL29620882 | 0.79 | TRPV1 (0.57) | TRPV1HDAC1HDAC6DGAT1FLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450281-A | Inhibitor compounds | 辛塞拉治疗私人有限公司 | 2022-05-06 | — | — | CN | disclosed |