Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9572453 | 0.83 | MEN1 (0.53) | KMT2AMEN1ALDH1A1KIF11LOXL2 | |
| SCHEMBL28940925 | 0.81 | CYP2D6 (0.46) | KMT2AMEN1KIF11LOXL2HDAC1 | |
| SCHEMBL15881349 | 0.79 | MEN1 (0.48) | KMT2AMEN1LOXL2 | |
| SCHEMBL28941077 | 0.78 | MEN1 (0.41) | KMT2AMEN1KIF11LOXL2 | |
| SCHEMBL28941045 | 0.78 | MEN1 (0.41) | KMT2AMEN1LOXL2GCK | |
| SCHEMBL28575456 | 0.78 | CHEK2 (0.44) | CHEK1IKBKBCHEK2HDAC1HDAC6 | |
| SCHEMBL28940998 | 0.77 | MEN1 (0.40) | KMT2AMEN1ABL1GCK | |
| SCHEMBL28723920 | 0.76 | GCK (0.40) | KMT2AMEN1CHEK2ABL1ALDH1A1 | |
| SCHEMBL28292605 | 0.76 | MEN1 (0.46) | KMT2AMEN1ALDH1A1KIF11 | |
| SCHEMBL28292630 | 0.76 | MEN1 (0.48) | KMT2AMEN1ALDH1A1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | claimed |
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |