SCHEMBL28940977

SCHEMBL28940977

Cc1cc(-c2nc3ccc(OCCOC(N)=O)cc3s2)c2ncc(OC(F)F)nc2c1

nearest known ligand 0.71

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 20/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21395367 0.88 F2RL3 (0.81) F2RL3
SCHEMBL21379599 0.88 F2RL3 (0.78) F2RL3
SCHEMBL21395563 0.88 F2RL3 (0.78) F2RL3
SCHEMBL30189835 0.88 F2RL3 (0.78) F2RL3
SCHEMBL21379572 0.87 F2RL3 (0.75) F2RL3
SCHEMBL19783345 0.83 F2RL3 (1.00) F2RL3
SCHEMBL19782738 0.83 F2RL3 (0.68) F2RL3
SCHEMBL19782870 0.81 F2RL3 (0.60) F2RL3
SCHEMBL19783076 0.81 F2RL3 (0.75) F2RL3
SCHEMBL30187504 0.81 F2RL3 (0.75) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109689647-B Bicyclic heteroaryl substituted compounds 百时美施贵宝公司 2023-01-20 CN claimed
CN-109689647-B Bicyclic heteroaryl substituted compounds 百时美施贵宝公司 2023-01-20 CN disclosed