Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.31 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28943542 | 1.00 | PTPN1 (0.31) | PTPN1UTS2RMALT1PDK2PDCD1 | |
| SCHEMBL19330432 | 0.95 | SERPINE1 (0.31) | MALT1PDK2 | |
| SCHEMBL19330434 | 0.95 | SERPINE1 (0.31) | MALT1PDK2 | |
| SCHEMBL19330430 | 0.95 | SERPINE1 (0.31) | MALT1PDK2 | |
| SCHEMBL28768737 | 0.89 | PTPN1 (0.34) | PTPN1UTS2RMALT1PDK2PDCD1 | |
| SCHEMBL21318471 | 0.89 | PTPN1 (0.34) | PTPN1UTS2RMALT1PDK2PDCD1 | |
| SCHEMBL19330500 | 0.85 | MALT1 (0.33) | PTPN1UTS2RMALT1PDK2 | |
| SCHEMBL19330498 | 0.85 | MALT1 (0.33) | PTPN1UTS2RMALT1PDK2 | |
| SCHEMBL28767620 | 0.85 | SERPINE1 (0.34) | PTPN1 | |
| SCHEMBL28767624 | 0.85 | SERPINE1 (0.34) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108778273-B | Bicyclic aryl monocyclic beta-lactam compounds and methods of use thereof for treating bacterial infections | 默沙东公司 | 2022-06-17 | — | — | CN | disclosed |